劈离式肝移植术后移植肝再生的研究

目的研究劈离式肝移植术后移植肝组织的再生规律。方法通过CT检查计算劈离式肝移植术后4例受体在不同时间点的肝体积变化,并检查患者移植术后肝功能。结果受体1术后4个月、1年时肝体积分别是标准体积的114%、97%,肝体积再生率为-11·0%、-24·3%;受体2术后4个月、1年肝体积分别是标准体积的96%、100%,肝体积再生率为24·4%、30·0%。受体3术后2个月肝体积是标准体积的86%,肝体积再生率为12·0%;受体4术后2个月肝体积是标准体积的90%,肝体积再生率为20·0%。4例受体术后肝功能均恢复正常。结论劈离式肝移植供肝有较强的再生能力,能满足受体的代谢需要。

Liver regeneration in recipients after split liver transplantation

Objective To study donor liver regeneration in recipients after split liver transplantation. Methods Liver volume regeneration was assessed by CT and hepatic function review. Results The graft to standard liver volume ratio of recipient one at POD120 and POD360 was 114%,97% with liver volume regeneration ratio of -11.0%,-24.3% respectively. For recipient two it was 96%,100% and 24.4%,30.0%,respectively. The graft to standard liver volume ratio of recipient three at POD60 was 86% with a regeneration ratio of 12.0%. For recipient four at POD60 it was 90% and 20.0% respectively. The hepatic function in all recipients became normal gradually. Conclusion The transplanted donor liver after split liver transplantation has strong ability of regeneration and is capable of normal hepatic function in the recipient.