| 结缔组织生长因子与后发性白内障的研究进展 |
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| 引用本文： | 卜文娟,徐国兴.结缔组织生长因子与后发性白内障的研究进展[J].国际眼科杂志,2008,8(12):2487-2489. |
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| 作者姓名： | 卜文娟 徐国兴 |
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| 作者单位： | 福建医科大学附属第一医院福建省眼科研究所,中国福建省福州市,350005 |
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| 基金项目： | 福建医科大学第一临床医学院学科带头人培养基金课题(No.2007-XKDT)~~ |
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| 摘 要： | 后发性白内障(又称后囊膜混浊)已成为白内障术后视力再度下降,影响术后远期视力恢复的突出问题,主要是由于残留的晶状体上皮细胞向后囊膜移行、增殖形成。结缔组织生长因子(connective tissue growth factor,CTGF)是近年来倍受关注的促纤维化细胞因子。本文对近年来CTGF与后发性白内障关系的研究进展综述如下。
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| 关 键 词： | 结缔组织生长因子 后发性白内障 |
Current advance on the relationship of connective tissue growth factor and posterior capsule opacification |
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| Wen-Juan Bu,Guo-Xing Xu.Current advance on the relationship of connective tissue growth factor and posterior capsule opacification[J].International Journal of Ophthalmology,2008,8(12):2487-2489. |
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| Authors: | Wen-Juan Bu Guo-Xing Xu |
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| Institution: | The First Affiliated Hospital of Fujian Medical University,Fujian Institute of Ophthalmology,Fuzhou 350005,Fujian Province,China |
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| Abstract: | Posterior capsule opacification (PCO) is a predominant problem after modern extracapsular cataract surgery and phacoemulsification with intraocular lens implication. Some residual lens epithelial cells maybe migrate and proliferate toward to posterior capsule,and then lead to the occurrence of PCO. Connective tissue growth factor (CTGF) is a critical mediator during the fibrosis of tissue and organ. The aim of us is to summarize the relationship between CTGF and PCO in recent years. |
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| Keywords: | connective tissue growth factor posterior capsule opacification |
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