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青蒿琥酯抗肿瘤作用观察
引用本文:王胜伟,张仲苗,章荣华.青蒿琥酯抗肿瘤作用观察[J].中药药理与临床,2005,21(5):12-13.
作者姓名:王胜伟  张仲苗  章荣华
作者单位:1. 浙江省金华市中医院药剂科,金华,321017
2. 浙江大学医学院附属第二医院药剂科,杭州,310009
3. 浙江省疾病预防控制中心毒理实验室,杭州,310009
摘    要:目的:对抗疟药青蒿琥酯进行抗肿瘤活性实验研究.方法:采用体内抗肿瘤实验方法,观察青蒿琥酯对小鼠移植性肿瘤的抑制作用.结果:青蒿琥酯能明显的抑制小鼠移植性S180肉瘤的生长,延长艾氏腹水瘤小鼠的生存时间.结论:青蒿琥酯对小鼠移植性肿瘤具有明显的抑制作用.

关 键 词:青蒿琥酯  移植性肿瘤  小鼠

Study of artesunate on antineoplastic effects
Wang Shengwei,Zhang Zhongmiao,Zhang Ronghua.Study of artesunate on antineoplastic effects[J].Pharmacology and Clinics of Chinese Materia Medica,2005,21(5):12-13.
Authors:Wang Shengwei  Zhang Zhongmiao  Zhang Ronghua
Institution:The Traditional Chinese Medicine Hospital of Jinhua City, Jinhua 321017
Abstract:Objective: To study the antineoplastic effects of artesunate in mice.Method: The inhibition of growth on mice transplanted cancer was observed by antineoplastic experiments in vivo.Results: Artesunate can obviously inhibit the growth of the mice transplanted S_(180) sarcoma and prolong the survival period of EAC mice.Conclusion: Artesunate has a distinct antineoplastic effects on mice transplanted cancer.
Keywords:artesunate  transplanted cancer
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