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抗瘤酮类似物的抗肿瘤活性
引用本文:李正化.抗瘤酮类似物的抗肿瘤活性[J].华西药学杂志,1990,5(3):129-132.
作者姓名:李正化
作者单位:华西医科大学药学院,华西医科大学药学院,四川省肿瘤医院肿瘤研究所,四川省肿瘤医院肿瘤研究所 成都 610041,成都 610041
摘    要:本文报道15个抗瘤酮A_(10)衍生物对临床分离的六株肿瘤的抑制活性测定结果,比较了它们同临床常用抗癌药物对临床分离的食道癌89111的抑制活性,并对比测定了化合物4、7和9同抗瘤酮A_1。对小鼠S_(160)瘤株的抑制活性。

关 键 词:抗瘤酮  抗瘤酮类似物  抗肿瘤活性

THE ANTITUMOR ACTIVITIES OF ANTINEOPLASTON ANALOGUES
Guo Daming,Li Zhenghua,Lu Shaoping,Dong Yulin School of Pharmacy,West China University of Medical Sciences Chengdu The Institute of Oncology,Sichuan Tumor Hospital.THE ANTITUMOR ACTIVITIES OF ANTINEOPLASTON ANALOGUES[J].West China Journal of Pharmaceutical Sciences,1990,5(3):129-132.
Authors:Guo Daming  Li Zhenghua  Lu Shaoping  Dong Yulin School of Pharmacy  West China University of Medical Sciences Chengdu The Institute of Oncology  Sichuan Tumor Hospital
Abstract:In this paper, we rep- ort the in vivo antitumor activities of 15 Antineoplaston A_(10) analogues against six strain tumors separated from clinic. Their activity against one strain of eso- phagus cancer were compared with Cyc- lophosphamide, 5-Fluorouracil, Metho- troxate and Vinblastine. The inhibition activties of 3 compounds as well as Ant- ineoplaston A_(10) against Sarcoma-180 we- re reported.
Keywords:Anineeplasten A_(10) Antineoplaston Analogues
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