| 均匀设计法优化穿心莲的提取工艺 |
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| 引用本文： | 刘蕾,许笑笑,韩光. 均匀设计法优化穿心莲的提取工艺[J]. 河南大学学报(医学版), 2006, 25(4): 33-35 |
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| 作者姓名： | 刘蕾 许笑笑 韩光 |
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| 作者单位： | 河南大学药学院,天然药物研究所,河南,开封,475001;河南大学药学院,天然药物研究所,河南,开封,475001;河南大学药学院,天然药物研究所,河南,开封,475001 |
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| 摘 要： | 目的:优化穿心莲提取的工艺条件。方法:采用均匀设计优选穿心莲提取工艺;以穿心莲内酯和脱水穿心莲内酯的含量为指标,考察药材的提取时间、温度、溶媒量、醇浓度等因素对提取工艺的影响。结果:穿心莲最佳提取工艺为3倍量75%乙醇,40℃提取3次,每次提取2 h。结论:优选的穿心莲提取方法简单易行,适合工业化生产。
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| 关 键 词： | 均匀设计 穿心莲 提取工艺 |
| 文章编号： | 1672-7606(2006)04-0033-03 |
| 收稿时间： | 2006-10-11 |
| 修稿时间： | 2006-10-11 |
Optimizing the Extraction Process of Andrographis Panniculata by Uniform Design |
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| LIU Lei,XU Xiao-xiao,HAN Guang. Optimizing the Extraction Process of Andrographis Panniculata by Uniform Design[J]. Journal of Henan University, 2006, 25(4): 33-35 |
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| Authors: | LIU Lei XU Xiao-xiao HAN Guang |
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| Affiliation: | Institute of Natural Produce of Pharmacy College, Henan University, Henan Kaifeng 475001, China |
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| Abstract: | Objective: To optimize the extraction process of Andrographolide Panniculata.Methods: The extraction process was investigated using uniform design,with the content of andrographolide and 14-deoxy-11-oxoandrographolide as the detecting index.Results: The exacting process were optimized as follows :the drug was extracted three times for two hour with three fold volume of 75% ethanol in 40 ℃.Conclusion: The optimized procedure is simple and easy to do,it is suitalle for industrial production. |
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| Keywords: | Andrgrapholide Panniculata Uniform Design Extraction Process |
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