二补助育汤对子宫内膜容受性影响的临床研究

目的:观察二补助育汤对子宫内膜容受性的影响。方法:收集从2010年5月-2011年5月因子宫内膜容受性低造成体外受精-胚胎移植(IVF-ET)失败而就诊于肖承悰教授门诊的肾虚型患者42例,服用二补助育汤3个月,随访治疗半年后受孕率和统计治疗前后临床症状积分、子宫内膜厚度及雌、孕激素水平的变化。结果:半年随访受孕率为57.1%;治疗后临床症状积分较治疗前有显著改善(P<0.05);治疗后HCG注射日子宫内膜厚度明显大于治疗前(P<0.05),且雌激素水平较治疗前显著升高(P<0.05);孕激素水平治疗前后比较无统计学意义(P>0.05)。结论:二补助育汤对改善子宫内膜容受性有较显著的疗效。

Impact of Erbu Zhuyu Decoction on Endometrial receptivity

Objective:To observe the impact of Erbu Zhuyu Decoction on endometrial receptivity.Methods:42 patients,who with kidney deficiency,had failed in in-vitro fertilization-embryo transfer(IVF-ET) due to lower endometrial receptivity,then see doctor Xiao Chengcong from May 2010 to May 2011,took Erbu Zhuyu Decotion for 3 months.We calculated pregnancy rates during six months follow ups,observed changes in clinical syndrome score,endometrial thickness,estrogen and progesterone levels.Results:During six months follow ups,pregnancy rate was 57.1% ;clinical symptoms were significantly relieved(P < 0.05) ;endometrial thickness on HCG injection was significantly greater than before treatment(P < 0.05),and estrogen levels were significantly higher than before treatment(P < 0.05) ;Progesterone levels before and after treatment was not significantly changed(P > 0.05).Conclusion:Erbu Zhuyu Decoction can significantly improve endometrial receptivity.