支气管镜下高频联合化疗治疗老年非小细胞肺癌的疗效观察

目的:观察支气管镜下高频电刀术联合全身化疗治疗老年中央型非小细胞肺癌(NSCLC)患者的疗效。方法:将38例老年中央型非小细胞肺癌患者随机分为治疗组和对照组,每组各19例。治疗组患者行支气管镜下高频电刀烧灼切割术,并给予化疗,对照组单用化疗,2组化疗方案相同。比较2组患者气促分级、Karnofsky评分(KPS)、肺功能改善程度以及近期、远期疗效。结果:治疗组气促分级、肺功能、KPS评分改善明显优于对照组。治疗组完全缓解1例,部分缓解15例,有效率明显高于对照组(84.2%vs 57.9%,P<0.05)。治疗组中位生存时间,0.5年、1年生存率明显高于对照组(P<0.05)。结论:经支气管镜下高频电刀术联合化疗可有效解除气道阻塞,提高患者生活质量,近期疗效显著,中位生存时间、1年生存率提高,值得临床推广。

Bronchoscope under high frequency electric sabreplay chemotherapy curative effect observation of treatment of senile non-small cell lung cancer

abstract] objective: to observe the bronchoscope under high frequency electric sabreplay joint systemic chemotherapy to treat senile central type the curative effect of patients with non-small cell lung cancer (NSCLC).Methods: 38 cases of elderly patients with central type of non-small cell lung cancer were randomly divided into treatment group and control group.Treatment group bronchoscopy was performed under the high frequency electricity knife cutting, burning and giving chemotherapy and chemotherapy alone in the control group, two groups of the same chemotherapy regimens.Compare two groups of patients with shortness of breath grading, KPS change, improve lung function and the recent curative effect evaluation, the comparison of the long-term curative effect.Results: the treatment group shortness of breath grading, pulmonary function, KPS score improved significantly better than the control group.Treatment group (19 cases), 1 case of complete remission, partial in 15 cases, efficient (84.21%), significantly higher than the control group (57.89%) (P < 0.05).Treatment group (a median survival time is 0.5 years, 1 year survival rate is significantly higher than the control group, comparing differences between the two groups was statistically significant (P < 0.05).Conclusion: the high frequency electric bronchoscope sabreplay MDT can effectively relieve airway obstruction, improve patient quality of life, the recent curative effect is distinct, the median surial, one year survival rate increased, worth clinical promotion.