Red Blood Cell Antibody Screening with Groupamatic System |
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| Authors: | S Confida C Hurel N Chesnel M Garretta and A Muller |
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| Institution: | Centre National de Transfusion Sanguine, Orsay, France |
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| Abstract: | Abstract. The trypsin-polybren-citrate (TPC) technique is based on Lalezari's method and has been developed on the Groupamatic equipment to allow the screening of irregular alloantibodies which are not detectable on this machine by the present routine techniques. TPC screening has two main advantages: it gives more reliable results for Rh, Kell, Lewis and P antibodies than bromelin-methyl-cellulose, and it permits the screening of Duffy and Kidd antibodies. However, although the TPC technique contributes to an improved quality of the automated screening of blood donor samples, it should not be used as the only method when recipient samples are concerned. |
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