2型糖尿病患者血清超敏C反应蛋白及血脂检测的临床意义

目的探讨血清超敏C反应蛋白(hs-CRP)和血脂在2型糖尿病患者诊断中临床意义。方法观察80例2型糖尿病患者(观察组)和50例健康体检者(对照组)血清hs-CRP、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平。分析观察组hs-CRP与血脂各项检测指标的相关性。结果与对照组比较,观察组血清TC、TG、LDL-C、hs-CRP水平明显高于对照组(P<0.01),HDL-C水平明显低于对照组(P<0.01)。观察组hs-CRP与TC、TG、LDL-C呈正相关(P<0.05或P<0.01),与HDL-C呈负相关(P<0.01)。结论血脂与炎症因子水平检测是糖尿病诊断的有效手段。

Clinical significance of serum high sensitivity C- reactive protein and serum lipids in patients with type 2 diabetes mellitus

Objective To investigate the clinical diagnostic significance of the high sensitivity C-reactive protein(hs-CRP) and serum lipids in patients with type 2 diabetes mellitus(T2DM).Methods The hs-CRP,total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),and high density lipoprotein cholesterol(HDL-C) levels in T2DM patients(observation group,n=80) and healthy patients(control group,n=50) were observed.The correlation between hs-CRP and serum lipids in the observation group was analyzed.Results Compared with the control group,the serum TC,TG and LDL-C,hs-CRP levels were significantly higher(P<0.01),and HDL-C levels were significantly lower in the observation group(P<0.01).In the observation group,hs-CRP was positively correlated with TC,TG and LDL-C(P<0.05 or P<0.01),and negatively correlated with HDL-C(P<0.01).Conclusion Serum lipids and hs-CRP are effective means in diagnosis of T2DM.