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养血清脑颗粒对慢性脑供血不足患者失眠和认知功能改善作用的临床评价
引用本文:李泽锋,梁俊迪,何艳,刘秀萍,曾瑛. 养血清脑颗粒对慢性脑供血不足患者失眠和认知功能改善作用的临床评价[J]. 中国医药指南, 2010, 8(22): 30-32
作者姓名:李泽锋  梁俊迪  何艳  刘秀萍  曾瑛
作者单位:广东肇庆医学高等专科学校附属医院神经内科,526020
摘    要:目的观察养血清脑颗粒对慢性脑供血不足患者失眠的疗效和认知功能的改善作用。方法对136例慢性脑供血不足患者按就诊时间顺序分为对照组(复方丹参片组)和治疗组(养血清脑颗粒组)各68例,分别观察两组患者用药前和用药2个月后失眠(用阿森斯失眠量表评定疗效)和认知功能(MMSE积分、HDS积分的测评)的改善情况,并进行对比分析。结果治疗组患者的失眠临床疗效显著,症状AIS评分明显降低;认知功能也较治疗前有显著改善,MMSE积分、HDS积分的测评均明显提高,两组间相比差异具有统计学意义(P<0.01、P<0.05)。结论服用养血清脑颗粒能有效地改善慢性脑供血不足患者的失眠和认知功能,疗效确切,用药简便、安全无毒。

关 键 词:养血清脑颗粒  慢性脑供血不足  失眠  认知功能障碍  临床疗效

Clinical Evaluation of Yangxue Qingnao Granule in Treating Chronic Cerebral Circulation Insuficiency on Insomnia and Cognitive Function
LI Ze-feng,LIANG Jun-di,HE Yan,LIU Xiu-ping,ZENG Ying. Clinical Evaluation of Yangxue Qingnao Granule in Treating Chronic Cerebral Circulation Insuficiency on Insomnia and Cognitive Function[J]. Guide of China Medicine, 2010, 8(22): 30-32
Authors:LI Ze-feng  LIANG Jun-di  HE Yan  LIU Xiu-ping  ZENG Ying
Affiliation:(Department of Neurology,The Affiliated Hospital of Zhaoqing Medical College,Zhaoqing 526020,China)
Abstract:Objective To observe the clinical efficacy of Yangxue Qingnao Granule on insomnia and cognitive function in the treatment of chronic cerebral circulation isufficiency(CCCI).Methods 80 CCCI patients were equally randonfized to two groups by the time:the study group was treated with Yangxue Qingnao Granule,and the control group with compound Danshen Tablet,both was 68 cases.Observed the efficacy on insomnia(evaluated with Arson's Insomnia Scale)and cognitive function(tested with MMSE score,HDS integral evaluation)before the treatment and 2 months after the medication,and analysised comparatively.Results The efficacy on insomnia in the study group was significant,symptoms of AIS score decreased significantly,and the cognitive function improved significantly,MMSE score,HDS evaluation points were improved markedly.Conclusions Yangxue Qingnao Granule can improve effectively on insomnia and cognitive in the treatment of Chronic Cerebral Circulation Insuficiency,has an exact efficacy.The use is simple,safe and non-toxic.
Keywords:Yangxtle Qingnao granule  Chronic cerebral circulation insuficiency  Insomnia  Dysfunction in cognition  Clinical efficacy
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