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抑郁症患者治疗中脑内神经递质的变化
引用本文:宋志强,简冶拉,王玉超,刘兰香.抑郁症患者治疗中脑内神经递质的变化[J].青海医药杂志,2006,36(8):10-11.
作者姓名:宋志强  简冶拉  王玉超  刘兰香
作者单位:青海省第三人民医院,810007
摘    要:目的:观察抑郁症患者治疗前后脑内神经递质的变化。方法:对入组的30例患者用脑电超慢涨落分析仪在治疗前后的不同阶段对神经递质含量进行检测。结果:抑郁症患者脑内神经递质(尤其是5-HT及NE)降低,治疗2周后NE值明显回升(P〈0.05),治疗6周后5-HT及NE显著上升(P〈0.01)。结论:抑郁症患者脑内5-HT及NE含量降低,随着药物治疗和症状的改善,患者脑内5-HT及NE含量逐步升高。

关 键 词:抑郁症  神经递质  脑电超慢涨落分析

Therapeutic Changes of Brain Brain Neurotransmiters in Depression
Song Zhiqiang,Jian Yela,Wang Yuchao,Liu Lanxiang.Therapeutic Changes of Brain Brain Neurotransmiters in Depression[J].Qinghai Medical Journal,2006,36(8):10-11.
Authors:Song Zhiqiang  Jian Yela  Wang Yuchao  Liu Lanxiang
Abstract:Objective: To observe the changes of brain neuroregulator in patients with depression after treatment.Methods: 30 patients with depression were enrolled in this report.The level of 5-HT and NE was measured before and after treatment by Encephalofluctuograph technology.Results: The level of brain neurotransmitors,such as 5-HT and NE,was decreased before treatment;but the level of NE was increased after 2 weeks treatment(P<0.05) and the 5-HT and NE were significantly increased after 6 weeks treatment(P<0.01).Conclusions: The brain level of 5-HT and NE is decreased in the patients with depression but its level can increase when the patients are treated and improve their symptoms.
Keywords:Depression  5-HT  NE  Neurotransmiters  Brain  Treatment  Encephalofluctuograph
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