硬膜外注入罗哌卡因和肌注度冷丁在中孕引产镇痛中的应用研究

目的比较PCA(患者自控)注药镇痛泵连续硬膜外注入盐酸罗哌卡因和度冷丁肌注在中孕引产镇痛中的效果。方法将131例要求终止中期妊娠的孕妇随机分为盐酸罗哌卡因组(A组)、度冷丁组(B组)和对照组(C组),观察比较3组的产痛程度,产后2h内出血量、羊膜腔注入利凡诺至排胎所需时间以及不良反应。结果A组和B组的产痛强度明显低于C组(P<0.01),A组产痛强度低于B组。镇痛效果A组100%,B组57.5%,C组为0,差异有级显著意义(P<0.01)。3组之间产后出血量、排胎时间无差异(P>0.05)。结论使用PCA注药镇痛泵注入盐酸罗哌卡因镇痛和使用度冷丁肌注引产镇痛不影响排胎过程,对患者无不良影响,但镇痛效果PCA镇痛泵注入盐酸罗哌卡因优于肌注度冷丁,值得推广应用。

The Study of Application of Epidural Infusion of Ropivacaine and Pethidine Intramuscular Injection in Induction of Labor Analgesia in Midpregnancy

Objective To compare the effects of patient-controlled continous epidural infusion of ropivacaine and pethidine intramuscular injection in induction of labor analgesia in midpregnancy.Methods 131 pregnant who ask for induction of labor were randomly divided into 3 groups: group A, patient-controlled epidural analgesia (PCEA) with 0.1% ropivacaine fentanyl citrate 2ug/ml; group B,pethidine intramuscular injection; Group C, without PCEA and pethidine as a control. Pain level,bleeding quantity in 2 hours after induction of labor,the time of fetus laboring,and side effects were investigated and compared.Results The pain level of group A and B were remarkably lower than ther of group C (P<0.01), The pain level of group A was more lower than group B(P<0.01).The quantity of bleeding after induction of labor and the time of fetus laboring aming 3 group were not different respectively (P>0.05).Conclusions PCEA with ropivacaine and pethidine intramuscular injection in induction of labor analgesia in midpregnancy did not affect fetus laboring and had no side effects. But the former was more effective than the latter, it was worthy to popularise this method.