| Wnt信号通路与消化道肿瘤关系的研究进展 |
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| 引用本文： | 杨升,卢辉山. Wnt信号通路与消化道肿瘤关系的研究进展[J]. 世界华人消化杂志, 2007, 15(27): 2880-2884 |
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| 作者姓名： | 杨升 卢辉山 |
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| 作者单位： | 福建医科大学附属协和医院肿瘤科,福建省福州市,350001;福建医科大学附属协和医院肿瘤科,福建省福州市,350001 |
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| 摘 要： | Wnt信号通路对控制胚胎发育起着重要作用,其异常激活参与了人类多种肿瘤的发病过程,与消化道肿瘤有着密切关系.而Wnt信号通路的拮抗剂能阻滞信号转导,抑制Wnt2信号通路的异常激活,可望为将来抗肿瘤治疗提供一条新的途径.
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| 关 键 词： | Wnt信号转导 消化道肿瘤 |
| 收稿时间： | 2007-06-14 |
| 修稿时间： | 2007-09-13 |
Progress of research on the relationship between Wnt signal transduction and digestive tract tumors |
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| Sheng Yang,Hui-Shan Lu. Progress of research on the relationship between Wnt signal transduction and digestive tract tumors[J]. World Chinese Journal of Digestology, 2007, 15(27): 2880-2884 |
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| Authors: | Sheng Yang Hui-Shan Lu |
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| Abstract: | The Wnt signal transduction pathway plays an important role in controlling embryo development;its abnormal elevation is involved in many types of human tumorigenesis,and it has a close relationship with digestive tract tumors.Wnt antagonists can block Wnt signal transduction and inhibit its abnormal elevation, and therefore may provide a potential new anti- cancer therapy. |
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| Keywords: | Wnt signal transduction Digestive tract tumor |
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