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Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis |
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| Authors: | Kim Soo Ki Takeda Haruhiko Takai Atsushi Matsumoto Tomonori Kakiuchi Nobuyuki Yokoyama Akira Yoshida Kenichi Kaido Toshimi Uemoto Shinji Minamiguchi Sachiko Haga Hironori Shiraishi Yuichi Miyano Satoru Seno Hiroshi Ogawa Seishi Marusawa Hiroyuki |
| Affiliation: | 1.Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan ;2.Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan ;3.Department of Gastroenterology and Hepatology, Kobe Asahi Hospital, Kobe, Japan ;4.Department of Omics-Based Medicine, Center for Preventive Medicine, Chiba University, Chiba, Japan ;5.Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan ;6.Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan ;7.Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan ;8.Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka, Japan ; |
| Abstract: | Journal of Gastroenterology - Hepatocellular carcinoma (HCC) recurrently develops in cirrhotic liver containing a number of regenerative nodules (RNs). However, the biological tumorigenic potential... |
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