A Case of Herpetic Keratitis after Subconjunctival Triamcinolone Acetonide Injection期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A Case of Herpetic Keratitis after Subconjunctival Triamcinolone Acetonide Injection

Authors:	Hidenori Inoue Takashi Suzuki Takeshi Joko Tomoyuki Inoue Yuichi Ohashi

Affiliation:	Department of Ophthalmology, Ehime University, Graduate School of Medicine, Toon, Japan

Abstract:	Purpose We report a case of herpetic epithelial keratitis that developed after subconjunctival triamcinolone acetonide injection (STI). Methods A 65-year-old female with anterior uveitis and hypotony in her right eye was given a STI (2 mg/0.5 ml). After the injection, she developed redness and an ocular discharge. A clinical examination was performed and real-time polymerase chain reaction (PCR) was used to amplify the viral DNA in a corneal scraping. Results Slit-lamp biomicroscopy revealed a severe purulent discharge, conjunctival injection, and a geographic corneal ulcer in the right eye. Herpes simplex virus 1 DNA was identified in the corneal scraping using real-time PCR. Herpetic keratitis was diagnosed and topical acyclovir ointment as well as systemic valacyclovir were started. The inflammation subsided with this medication. Conclusion We encountered a case of herpetic epithelial keratitis after a STI.Key words: Herpetic keratitis, Subconjunctival triamcinolone acetonide injection, Anterior uveitis, Polymerase chain reaction, Hypotony

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