88例肝病患者CHE、TBA以及PT测定结果分析

为了解血清中CHE活性、TBA含量以及PT测定与各类肝脏疾病的关系 ,对 88例经临床确诊为各类型肝病患者血清CHE、TBA以及PT测定结果进行分析 ,结果表明 :各类肝脏疾病TBA、PT均增高 ,CHE活性均降低 ,与正常对照组相比 ,除CHE指标差异无显著性外 ,其余各组差异有高度显著性 (P均 <0 .0 0 1) ,同时可以看到 ,慢性肝炎与肝硬化组的PT测定值差异无显著性 ,其余各组间此三项指标比较差异有显著性 ,P均为 0 .0 5～ 0 .0 0 1,提示血清CHE、TBA及PT测定对肝脏疾病的诊断均有较高的敏感性 ,均可作为评价肝病轻重程度的判断指标

Determination of CHE, TBA and PT in patients with liver disease: a report of 88 cases

In order to investigate the relationship between serum cholinesterase (CHE) activity. Serum Total Bile Acid (TBA) content, Total Bile Acid (PT) determination and various liver diseases, the results of serum CHE, TBA and PT in 88 patients diagnosed with various liver disease were analyzed. Results showed that both TBA and PT in liver disease increased, and CHE activity decreased. In comparison with the control group, everything except the CHE index differences, the differences of the other groups were significant (P<0.001). The study also found that there was no statistical difference in PT determination value between the chronic hepatitis group and cirrhotic group. There were significant differences between these three indexes in the other groups (all the P values were from 0.05 to 0.001). This study indicates that the values of serum CHE, TBA and PT can be used as indices to evaluate the degree of liver diseases.