11省市队列人群代谢综合征的流行病学研究

目的　探讨队列人群代谢综合征的流行病学特征。方法　在 1992年对 11省市队列人群 (35～ 6 4岁 ) 2 7739人进行基线危险因素的调查。计算队列人群代谢综合征患者各种因素的均值±标准差和标化患病率。结果　 (1) 11省市队列人群有代谢综合征者高腰围的百分率最高 ,男性为89 0 % ,女性为 85 1%。其他主要指标 (除高密度脂蛋白 )男性均高于女性 ;(2 )代谢综合征患病率为13 3% ,其中男性为 12 7% ,女性为 14 2 % ,且随年龄的增加而增长 ;(3)多元logistic分析结果表明 ,腰围和糖尿病家族史是男性代谢综合征患者的危险因素 ,女性为腰围和高血压家族史。高密度脂蛋白增高是代谢综合征的保护因素。结论　 11省市队列人群代谢综合征患病率较高 ,腰围增大是代谢综合征重要的危险因素。

The prevalence of metabolic syndrome in a 11 provinces cohort in China

Objective To explore the prevalence feature of the metabolic syndrome in a cohort of 11 provinces in China Methods A cohort study was carried out in population of 27 739 subjects (age 35-64 years) The baseline survey for risk factor of cardiovascular disease was Completed in 1992 The prevalence rate, means and standard deviation of various risk factors associated with metabolic syndrome were analysis Results (1) The prevalence rate of high waist circumference was highest among the components in metabolic syndrome (89 0% in males and 85 1% in females to metabolic syndrome patients) (2) The prevalence rate of metabolic syndrome was 13 3%(12 7% in males, 14 2% in females, P <0 000 1), and it was increased with age (3) Multivariable logistic analysis showed that the risk factors of the metabolic syndrome were the waist circumference and familial history of diabetes mellitus in males; and the waist circumference and familial history of high blood pressure in females Conclusions The prevalence of metabolic syndrome was high in 11 provinces in China The high waist circumference would be an important factor in metabolic syndrome