天芎头风片质量标准研究 |
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引用本文: | 陈江,;李兴科,;王康,;徐桂超.天芎头风片质量标准研究[J].中国药业,2014(24):81-83. |
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作者姓名: | 陈江 ;李兴科 ;王康 ;徐桂超 |
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作者单位: | [1]武警陕西省总队医院,陕西西安710054; [2]西安新通药物研究有限公司,陕西西安710077 |
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摘 要: | 目的建立天芎头风片的质量标准。方法采用显微鉴别法对方中全蝎进行鉴别;采用薄层色谱法对方中川芎、延胡索进行定性鉴别;采用高效液相色谱法对天芎头风片中天麻素进行含量测定。结果全蝎的显微鉴别方法专属性强,简单可行。川芎、延胡索的薄层色谱鉴别方法斑点清晰,重现性好。天麻素进样量在0.44-1.31μg范围内与峰面积呈良好线性关系,r=0.999 5;平均回收率为99.76%,RSD=1.17%(n=6)。结论所建立的方法稳定、准确、重复性好,可用于天芎头风片的质量控制。
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关 键 词: | 天芎头风片 天麻素 质量标准 |
Quality Standard of Tianxiong Toufeng Tablets |
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Institution: | Chert Jiang, Li Xingke, Wang Kang, Xu Guichao( 1. Shaanxi Provincial Armed Police Corps Hospital, Xi' an, Shaanxi, China 71005d; 2. Xi' an Xintong Pharmaceutical Research Co. , Ltd. , Xi'an, Shaanxi, China 710077) |
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Abstract: | Objective To establish the quality standard for Tianxiong Toufeng Tablets. Methods Scorpio in this preparation was identified by the microscopic identification method; Ligusticum chuanxiong and Rhizoma corydalis were qualitatively identified by TLC; the gastrodin content was determined by HPLC. Results The microscopic identification method of scorpio was strongly specific,simple and feasible; the spots of TLC for identifying Ligusticum chuanxiong and Rhizoma corydalis were clear with good reproducibility. The sample size of gastrodin within the range of 0. 44- 1. 31 μg showed good linear relation with the peak area(r = 0. 999 5). The average recovery rate of gastrodin was 99. 76%,RSD = 1. 17%(n = 6). Conclusion The established methods are stable and accurate with good reproducibility,which can be used for the quality control of Tianxiong Toufeng Tablets. |
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Keywords: | Tianxiong Toufeng Tablets gastrodin quality standard |
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