| 白头翁与蛴螬不同配伍比例体外抗病毒作用研究 |
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| 引用本文： | 颜娓娓,徐佳馨,王继锋,崔真真,史晨晓,周长征. 白头翁与蛴螬不同配伍比例体外抗病毒作用研究[J]. 长春中医药大学学报, 2018, 0(3): 453-456. DOI: 10.13463/j.cnki.cczyy.2018.03.014 |
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| 作者姓名： | 颜娓娓 徐佳馨 王继锋 崔真真 史晨晓 周长征 |
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| 作者单位： | 山东中医药大学,济南,250300山东中医药大学药学院,济南,250300 |
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| 基金项目： | 山东省中医药抗病毒应用基础与关键技术及产业化课题(XTCX2014C01-04) |
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| 摘 要： | 目的探究白头翁与蛴螬配伍体外抗病毒效果,筛选最佳抗病毒配伍比例。方法应用水提醇沉法分别得到白头翁与蛴螬水提醇沉液,用大孔树脂法吸附,得到水1部位,将白头翁与蛴螬按1:9、2:8、3:7、4:6、5:5、6:4、7:3、8:2、9:1分别配伍,做体外抗病毒实验。结果白头翁与蛴螬配伍后整体抗EV-71效果优于抗呼吸道合胞病毒效果;其中,当白头翁:蛴螬=8:2时效果最好,TI=68.594。结论当白头翁:蛴螬=8:2时效果最好,TI=68.594,筛选方法最佳。
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| 关 键 词： | 白头翁 蛴螬 药物配伍 抗病毒 pulsatilla grub combination of traditional Chinese medicine vitro antiviral |
Study on the antiviral effect of pulsatilla and grub in different compatibility proportion |
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| YAN Weiwei,XU Jiaxin,WANG Jifeng,CUI Zhenzhen,SHI Chenxiao,ZHOU Changzheng. Study on the antiviral effect of pulsatilla and grub in different compatibility proportion[J]. Journal of Changchun College of Traditional Chinese Medicine, 2018, 0(3): 453-456. DOI: 10.13463/j.cnki.cczyy.2018.03.014 |
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| Authors: | YAN Weiwei XU Jiaxin WANG Jifeng CUI Zhenzhen SHI Chenxiao ZHOU Changzheng |
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| Abstract: | Objective To explore the in vitro antiviral effect of Pulsatilla and grub, screening the best antiviral compatibility proportion.Methods Using water extraction and alcohol precipitation method were obtained with pulsatilla and grub extract, macroporous resin adsorption, water 1 parts, combined pulsatilla and grub with 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, 9:1, do experiment in vitro.Results The overall effect of anti EV-71is better than that anti RSV effect and the best proportion of pulsatilla and grub is 8:2, TI=68.594.Conclusion The best effect was 68.594 when the grub was 8:2, and the screening method was the best. |
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