| 肿瘤辐射敏感性与细胞凋亡 |
| |
| 引用本文： | 朱光旭,王小华. 肿瘤辐射敏感性与细胞凋亡[J]. 国际放射医学核医学杂志, 2000, 24(2): 78-82 |
| |
| 作者姓名： | 朱光旭 王小华 |
| |
| 作者单位： | 400038 重庆, 中国人民解放军第三军医大学全军复合伤研究所 |
| |
| 摘 要： | 辐射敏感性是肿瘤细胞复杂的生物学现象,在辐射诱导的细胞反应中具有不同的组织细胞类型特异性。肿瘤瘤射敏感性与辐射诱导的细胞凋亡密切相关,并受P53及其相关蛋白、Bcl-2基因家族蛋白、Fas及神经鞘磷脂-神经酰胺介导的信号途径、caspases级联反应等调控。
|
| 关 键 词： | 辐射敏感性 细胞凋亡 信号途径 基因表达调控 |
| 收稿时间： | 2000-01-10 |
Tumor radiosensitivity and apoptosis |
| |
| ZHU Guang xu,Wang Xiao hua. Tumor radiosensitivity and apoptosis[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2000, 24(2): 78-82 |
| |
| Authors: | ZHU Guang xu Wang Xiao hua |
| |
| Affiliation: | Institute of Combined Injury, Third Military Medical University, Chongqing 400038, China |
| |
| Abstract: | Radiosensitivity is a complex phenomenon in tumor cells and there exist special biological effects in different types of tissues' cells in inadiation induced cell responses. Tumor radiosentivity is tightly connected with irradiation induced apoptosis and is regulated by many protein products of apoptosis related genes such as p53 and related proteins, Bcl 2 gene family proteins, Fas and sphingomyelin/ceramide mediated signalling pathways and caspases cascade etc. |
| |
| Keywords: | radiosensitivity apoptosis signaling pathway regulation of gene expression |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《国际放射医学核医学杂志》浏览原始摘要信息 |
|
点击此处可从《国际放射医学核医学杂志》下载全文 |
