| 儿童肾病综合征D-二聚体检测的临床意义 |
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| 引用本文： | 秦雪,詹灵凌,甘宝文. 儿童肾病综合征D-二聚体检测的临床意义[J]. 广西医科大学学报, 2000, 17(6): 1005-1006 |
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| 作者姓名： | 秦雪 詹灵凌 甘宝文 |
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| 作者单位： | 广西医科大学第一附属医院临床医学实验中心南宁 530021 |
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| 摘 要： | 目的:探讨儿童肾病综合征(NS)患者血浆D-二聚体(DD)水平变化的临床意义.方法:采用ELISA法检测28例NS患儿(其中单纯型16例,肾炎型12例)血浆DD含量及末梢血血小板计数(PLT),并与正常对照组进行比较,单纯型与肾炎型进行比较.结果:NS患儿的DD及PLT值均明显高于对照组,两组间有显著性差异(P＜0.01);肾炎型NS的DD水平也明显高于单纯型(P＜0.05).结论:血浆DD水平增高提示NS患儿有高凝状态,且与病情严重程度平行.因此,DD的检测对儿童NS的临床诊断及病情的判断具有一定的指导意义.
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| 关 键 词： | D-二聚体 肾病综合征 儿童 |
| 修稿时间： | 2000-06-01 |
THE CLINICAL SIGNIFICANCE OF DETERMINATION OF PLASMA DDIMER IN CHILDREN WITH NEPHROTIC SYNDROME [文摘要] |
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| Qin Xue,Zhan Lingling,Gan Baowen,et al. THE CLINICAL SIGNIFICANCE OF DETERMINATION OF PLASMA DDIMER IN CHILDREN WITH NEPHROTIC SYNDROME [文摘要][J]. Journal of Guangxi Medical University, 2000, 17(6): 1005-1006 |
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| Authors: | Qin Xue Zhan Lingling Gan Baowen et al |
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| Abstract: | To study the significance of changes of plasma DDimer(DD) levels in children with NSMethods:DDi mer and PLT were detected among 28 cases (16 were simple type,12 were nephrit is type) and normal control group with ELISAResults:The le vels of DD and PLT in NS were significantly higher than that in control group( P<0.01);and the DD levels in simple type were significantly higher than that in nephritis type (P<0.05)Conclusion:The incre ased levels of plasma DD indicated that NS have hypercoagulation state, i t had positive relationship with patients' state, which suggests that detectio n of DD is significant for the diagnosis and judgement state of NS |
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| Keywords: | D-Dimer nephrotic syndrome children |
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