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Drug-related lupus in a patient with rheumatoid arthritis under sulfasalazine treatment
Authors:Dr K Wildhagen  K Hartung  M Hammer  W Mau  R E Schmidt  H Deicher  H Zeidler
Institution:(1) Abt. Rheumatologie, Zentrum Innere Medizin, Medizinische Hochschule Hannover, K.-Gutschow-Str. 8, W-3000 Hannover 61, Germany;(2) Zentrum Innere Medizin, Abt. Immunologie und Transfusionsmedizin, Konstanty-Gutschow-Str. 8, W-3000 Hannover 61, Germany
Abstract:Summary The induction of lupus-like syndromes with the appearance of single-stranded DNA antibodies is a well-known complication of drug therapy. In this report we present a patient with an erosive seropositive rheumatoid arthritis developing the clinical and serological features of systemic lupus erythematosus including the occurrence of double-stranded DNA antibodies under sulfasalazine treatment.
Keywords:Sulfasalazine  Drug-Related Lupus  Systemic Lupus Erythematosus
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