分段式干预对乳腺癌患者新辅助化疗负性反应的应用研究

目的 探讨分段式干预对乳腺癌患者新辅助化疗负性反应的效果.方法 将我院2012年1月至2014年2月间收治的乳腺癌患者100例,均行新辅助化疗.随机分为观察组和对照组,各50例.对照组给予常规护理干预,观察组在对照组的基础上给予分段式干预.以QLQ-C30评分表和MCMQ问卷评分对患者干预后心理状况进行评估.结果 观察组患者QLQ-C30评分中躯体功能、角色功能、认知功能、情绪功能、社会功能、总生命质量的得分显著高于对照组（P＜0.05）,而疲乏、恶心呕吐、失眠、食欲丧失得分显著低于对照组（P＜0.05）;观察组MCMQ问卷评分中,面对得分显著高于对照组（P＜0.05）,屈服得分显著低于对照组（P＜0.05）.结论 分段式干预能有效改善患者的心理状态、提升生活质量及降低负性反应.

Application research of segmented intervention on negative reaction of patients with breast cancer undergoing neoadjuvant chemotherapy

Objective To investigate the efficacy of segmented intervention on negative reaction of patients with breast cancer undergoing neoadjuvant chemotherapy.Methods 100 patients with breast cancer undergoing neoadjuvant chemotherapy in our hospital from January 2012 to February 2014 were randomly divided into observation group and control group,50 cases in each group.Patients in control group were given routine nursing intervention,while patients in observation group were given segmented intervention on the basis of control group.After intervention,psychological status of two groups was evaluated by QLQ-C30 score sheet and MCMQ questionnaire.Results Scores of physical function,role function,cognitive function,emotional function,social function and total life quality in QLQ-C30 score of observation group were significantly higher than those of control group （P 〈 0.05）; scores of fatigue,nausea and vomiting,insomnia and appetite loss in observation group were significantly lower than those in control group （P 〈 0.05）.In MCMQ questionnaire score,facing score of observation group was significantly higher than that of control group （P 〈 0.05）,yielding score of observation group was significantly lower than that of control group （P 〈 0.05）.Conclusion Segmented intervention can effectively improve mental state,the quality of life and reduce negative reaction of patients.