| 低能量激光照射对颌骨新生作用的组织化学测定 |
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| 引用本文： | 王元银,陈乔尔,王银龙,何家才,刘文清,杨晨,程继光,徐文华,张娟,朱坤鹍,胡超. 低能量激光照射对颌骨新生作用的组织化学测定[J]. 安徽医科大学学报, 2008, 43(2): 160-162 |
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| 作者姓名： | 王元银 陈乔尔 王银龙 何家才 刘文清 杨晨 程继光 徐文华 张娟 朱坤鹍 胡超 |
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| 作者单位： | 安徽医科大学附属口腔医院腔外科,合肥,230032;安徽医科大学附属口腔医院腔外科口腔组织病理科,合肥,230032;中国科学院安徽光机所,合肥,230031 |
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| 摘 要： | 目的探讨低能量激光对于颌骨新生过程中成骨细胞增殖的影响。方法选择健康成年杂种狗5只,于两侧颏孔区形成骨折,右侧以低能量激光照射骨折区,每日一次10min(每日总剂量108J),持续12d,采用免疫组化抗体PCNA测量骨折边缘新生骨细胞增生量。结果两侧均有PCNA阳性反应细胞,右侧骨折缺损区正反应细胞大量增生,与左侧对照组相比差异有显著性(P<0.001)。结论低能量激光能刺激和促进骨新生,有利于骨折愈合。
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| 关 键 词： | 激光/治疗应用 骨再生 |
| 文章编号： | 1000-1492(2008)02-0160-03 |
| 修稿时间： | 2008-01-25 |
The PCNA study of the mandibular bone regeneration by low energy laser irradiation |
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| Wang Yuanyin,Chen Qiaoer,Wang Yinlong,et al. The PCNA study of the mandibular bone regeneration by low energy laser irradiation[J]. Acta Universitis Medicinalis Anhui, 2008, 43(2): 160-162 |
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| Authors: | Wang Yuanyin Chen Qiaoer Wang Yinlong et al |
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| Abstract: | Objective To study the effect of low energy laser irradiation on cellular proliferation of the mandibular fracture.Methods To detect the initial change.Five-beagle were used in this study,the had been fractured the bilateral mandibular.Low energy laser irradiation was applied on right side to irradiate the fractured area for 10 minutes per day for 12 days(total energy:108 J/d).Immunohistochemical staining of proliferating cell nuclear antigen(PCNA) was performed to evaluate celluar proliferation on bone margin.Results The bilateral fractured area have cellular proliferation,the laser irradiation group presented the higher cellular proliferation rate PCNA-Positive(P<0.001) than that of nonirradiation group.Conclusion The effect of study suggests that the low energy laser irradiation can stimulate and accelerate the bone regeneration. |
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| Keywords: | laser/therapeutic use bone regeneration |
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