婴儿晚发性VitK缺乏症76例临床分析

目的:了解该院收治的76例婴儿晚发性Vit K缺乏症的病因,探讨该病的预防方法,减少发病率,降低死亡率,减少存活残疾儿。方法:回顾分析了1991年3月-2003年8月收治的76例婴儿晚发性Vit K缺乏症病人的发病诱因、实验室检查及防治与转归等资料。结果:该组病例的病死率为14.47％,颅内广泛性出血和脑疝是造成死亡和后遗症的主要原因。结论:该病是可以预防的,患儿以单纯母乳喂养多见,感染和用药等是其重要的发病诱因,大力提倡孕妇和乳母口服Vit K,新生儿生后肌注Vit Kt,减少使用抗生素,可以减少Vit K缺乏症的发病率。

Clinical analysis on 76 cases of infants with postnatal vitamin K deficiency

By understanding the pathogeny of 76 hospitalization infants with postnatal vitamin K deficiency in this hospital to explore the preventive measures, reduce the incidence of disease and mortality and number of the survival handicapped children. Methods: The pathogeny, laboratory examination, prevention and prognosis of 76 infants with postnatal vitamin K deficiency from Mar 1991 to Aug 2003 were retrospectively analyzed. Results: The mortality of these infants was 14.47%. The main causes for death and sequela were encephalic diffused hemorrhage and cerebral hernia. Conclusion: This disease can bt prevented. For the infant patients fed by breast milk, infection and drug were the main inducements. The pregnant women and women in breast-feeding period taking orally vitamin K, the neonatal being injected vitamin K after born and reducing the use of antibiotic should be advocated, which to decrease the incidence of vitamin K deficiency.