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新型植入式胃电刺激器的刺激效果及组织相容性动物实验研究
作者姓名:Li Y  Yao S  Mai S  Yao L  Chen S  Zhang W  Guo W  Zhang C
作者单位:1. 北京协和医学院中国医学科学院,北京,100730;中日友好医院消化内科,北京,100029
2. 中日友好医院消化内科,北京,100029
3. 清华大学微电子学研究所,北京,100084
基金项目:首都医学发展科研基金,国家自然科学基金
摘    要:介绍一种新型胃电刺激器,通过动物实验,观察植入体内后的刺激效果,并观察植入部位的病理反应,探讨胃电刺激器的安全性和有效性,以及所用材料的组织相容性。结果表明.该仪器安全.能够减少动物的摄食量,所用材料组织相容性良好。

关 键 词:胃电刺激器  植入  组织相容性

Experimental study on the stimulating effect and the tissue compatibility of a new type of implanted gastric electrical stimulator
Li Y,Yao S,Mai S,Yao L,Chen S,Zhang W,Guo W,Zhang C.Experimental study on the stimulating effect and the tissue compatibility of a new type of implanted gastric electrical stimulator[J].Chinese Journal of Medical Instrumentation,2011,35(6):418-421.
Authors:Li Yanmei  Yao Shukun  Mai Songping  Yao Li  Chen Shaoxuan  Zhang Weishuo  Guo Wenjuan  Zhang Chun
Institution:Li Yanmei1,2,Yao Shukun2,Mai Songping3,Yao Li2,Chen Shaoxuan2,Zhang Weishuo2,Guo Wenjuan2,Zhang Chun3 1 Peking Union Medical College & Chinese Academy of Medical Sciences,Beijing 100730 2 Department of Gastroenterology,China-Japan Friendship Hospital,Beijing 100029 3 Institute of Microelectronics,Tsinghua University,Beijing 100084
Abstract:A new type of gastric electrical stimulator(GES) was introduced.After the stimulator was implanted in beagle dogs,its stimulating effects and the pathological changes at the implant site were observed to study the safety and efficacy of stimulator as well as the tissue compatibility of the materials used.The results showed that,this type of stimulator was safe and capable of inhibiting food intake of the dogs,and that the materials used had good tissue compatibility.
Keywords:gastric electrical stimulator  implant  tissue compatibility  
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