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氯霉素地塞米松搽剂的制备及其临床应用
引用本文:汪小敏,周宗立,邵祺,胡佳圆,韩庆东. 氯霉素地塞米松搽剂的制备及其临床应用[J]. 中国临床药学杂志, 2006, 15(6): 379-381
作者姓名:汪小敏  周宗立  邵祺  胡佳圆  韩庆东
作者单位:浙江省嘉兴市第二医院皮肤科,嘉兴,314000
摘    要:目的介绍氯霉素地塞米松搽剂的制备,及其在轻中度寻常痤疮中的疗效。方法制备氯霉素地塞米松搽剂,并对其进行质量控制。分析其与氯霉素搽剂在轻中度寻常痤疮治疗过程中的临床疗效。结果本品制作简便,质量符合《中国药典》要求,与氯霉素搽剂比较,本品对轻中度寻常痤疮的治疗疗效更佳、不良反应更少。结论本品制备工艺可靠,质量可控,对轻中毒寻常痤疮的治疗疗效佳,不良反应少,是寻常痤疮治疗的好选择。

关 键 词:氯霉素地塞米松搽剂  寻常痤疮  氯霉素搽剂
文章编号:1007-4406(2006)06-0379-03
收稿时间:2005-05-30
修稿时间:2005-05-30

Preparation and clinical application of chloramphenicol and dexamethasone liniment
Wang Xiaomin,Zhou Zongli,Shao Qi,Hu Jiayuan,Han Qingdong. Preparation and clinical application of chloramphenicol and dexamethasone liniment[J]. Chinese Journal of Clinical Pharmacy, 2006, 15(6): 379-381
Authors:Wang Xiaomin  Zhou Zongli  Shao Qi  Hu Jiayuan  Han Qingdong
Affiliation:Department of Dermatology and Venerology, Jinxing No.2 Hospital of Zhejiang Province, Jiaxing 314000, China
Abstract:AIM To introduce the preparation of chloramphenicol and dexamethasone liniment,and evaluate the efficacy of it in the treatment of mild to moderate acne vulgaris patients.METHODS The chloramphenicol and dexamethasone liniment was prepared;its quality was controlled.The efficacy of chloramphenicol and dexamethasone liniment was evaluated in the treatment of mild to moderate acne vulgaris patients.RESULTS The manufacturing technology of this product was simple and its quality was in accord with require of Pharmacopoeia of The People's Republic of China.The efficacy of it in the treatment of mild to moderate acne vulgaris patients was better and adverse drug reaction was less than chloramphenicol liniment.CONCLUSION The manufacturing technology of this product is reliable and its quality can be controlled.The efficacy of it in the treatment of mild to moderate acne vulgaris patients is good and its adverse drug reaction is little.This product will be a good choice in the treatment of acne vulgaris
Keywords:chloramphenicol and dexamethasone liniment  acne vulgaris  chloramphenicol liniment
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