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Syngeneic cerebral cortical tissue as a stimulator of immunogenesis in thymectomized mice
Authors:G. A. Belokrylov
Abstract:Experiments on CBA mice showed that homogenate of gray matter (cortex) of syngeneic brain contains components which restore the population of splenic T-cells in thymectomized animals and stimulate the immune response to sheep's red blood cells. Homogenate of white matter has much weaker activity; indeed it could be due to gray matter contaminating the preparation. Homogenate of syngeneic muscle tissue has no biological activity.Laboratory of General Immunology, Department of Microbiology and Immunology, Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR V. I. Ioffe.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 9, pp. 327–330, September, 1978.
Keywords:thymus  brain  cross-reacting antigens  stimulation of immunogenesis
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