Normothermic ex vivo renal perfusion |
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| Authors: | E. Dean Bair M.D. Thomas A. Borden M.D. Edward T. Peter M.D. |
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| Affiliation: | From the Division of Urology and the Department of Surgery, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA |
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| Abstract: | Results of a preliminary investigation to (1) ascertain the feasibility of prolonged normothermic perfusion of the kidney, (2) develop a satisfactory perfusion solution, and (3) promote altered immunogenicity of donor renal tissue are reported. Initially, increased perfusion pressures, decreased flow rates, and severe weight gains were encountered. Addition of protein and manipulation of oxygen concentration in the perfusate greatly improved these parameters, but did not appear to improve viability of transplanted organs. |
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