| 同步放化疗与序贯放化疗对中晚期宫颈癌疗效的对比研究 |
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| 引用本文： | 张震,彭红华,张曦.同步放化疗与序贯放化疗对中晚期宫颈癌疗效的对比研究[J].中国医药导报,2011,8(14):30-31. |
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| 作者姓名： | 张震 彭红华 张曦 |
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| 作者单位： | 中南大学湘雅三医院肿瘤科,湖南长沙,410013 |
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| 摘 要： | 目的：探讨同步放化疗与序贯放化疗对中晚期宫颈癌的临床疗效。方法：将86例中晚期宫颈癌患者分为同步放化疗组（46例）和序贯放化疗组（40例），比较两组患者临床疗效、生存率及并发症。结果：化疗结束后同步放化疗组与序贯放化疗组患者治疗有效率分别为91.3％、87．5％，差异无统计学意义（P〉O．05）；同步放化疗组与序贯放化疗组4年生存率分别为84．8％、70．O％，差异有统计学意义（P〈O．05）；同步放化疗组盆腔复发率和远处转移率分别为4．3％、4.3％，显著低于序贯放化疗组的15．0％、12．5％，差异有统计学意义（P〈O．05）；两组并发症主要为骨髓抑制及消化道反应，两组均可耐受。结论：与序贯放化疗相比，同步放化疗治疗中晚期宫颈癌可提高患者4年生存率，减少局部复发率及远处转移率，且不良反应可耐受。
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| 关 键 词： | 中晚期宫颈癌 同步放化疗 序贯放化疗 |
A contrastive study on concurrent chemoradiotherapy and sequential chemoradiotherapy for advanced cervical cancer |
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| ZHANG Zhen,PENG Honghua,ZHANG Xi.A contrastive study on concurrent chemoradiotherapy and sequential chemoradiotherapy for advanced cervical cancer[J].China Medical Herald,2011,8(14):30-31. |
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| Authors: | ZHANG Zhen PENG Honghua ZHANG Xi |
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| Institution: | Department of Oncology,the Third Xiangya Hospital of Central South University,Hu′nan Province,Changsha 410013,China |
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| Abstract: | Objective:To explore the clinical effect of concurrent chemoradiotherapy and sequential chemoradiotherapy for advanced cervical cancer.Methods:86 cases with advanced cervical cancer were randomly divided into concurrent chemoradiotherapy group(46 cases) and sequential chemoradiotherapy group(40 cases).The clinical effect,survival rate and complications were analyzed in two group.Results:The local contral were 91.3% and 87.5% in concurrent chemoradiotherapy group and sequential chemoradiotherapy group respec... |
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| Keywords: | Advanced cervical cancer Concurrent chemoradiotherapy Sequential chemoradiotherapy |
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