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蒙药荜茇三味胶囊提取工艺的研究
引用本文:王烈群,那顺朝克图,张欣,刘宏婧,白广翠.蒙药荜茇三味胶囊提取工艺的研究[J].中国民族医药杂志,2010,16(2):37-39.
作者姓名:王烈群  那顺朝克图  张欣  刘宏婧  白广翠
作者单位:内蒙古医学院药学院,内蒙古,呼和浩特,010059
摘    要:目的:优选蒙药荜茇三味胶囊的提取条件。方法:采取正交实验法,用高效液相色谱法,以测定提取物中胡椒碱的含量为指标,考察乙醇浓度(A)、乙醇用量(B)、提取时间(C)、提取次数(D)等4个条件对提取效果的影响;进行四因素三水平试验。结果:实验设计因素中乙醇用量的影响最为显著。结论:荜茇三味胶囊的最佳提取工艺条件为A_1B_1C_1D_2,即每次加入药材6倍量的65%乙醇,提取2次,每次提取60min。

关 键 词:蒙药荜茇三味胶囊  胡椒碱  正交试验  提取工艺

Extraction craft research of Mongolian drug piperine three taste capsule
Wang Liequn,Nashun Chaoketu,Zhang Xin,Liu HongJing,Bai guangcui.Extraction craft research of Mongolian drug piperine three taste capsule[J].Journal of Medicine & Pharmacy of Chinese Minorities,2010,16(2):37-39.
Authors:Wang Liequn  Nashun Chaoketu  Zhang Xin  Liu HongJing  Bai guangcui
Institution:(Inner Mongolian medical college pharmacy specialty, Huhhot 010059)
Abstract:Goal:The option of Mongolian drug piperine three taste capsule extraction condition. Method:Adopt the orthogonal experiment method, with the high performence liquid chromatography, determine the content of piperine in the extraction as the target, inspect four conditions which influence the effect, including the ethyl alcohol density(A), ethyl alcohol amount used(B), extraction time(C), extraction number of times (D) ; Carry on four factor three level experiments. Finally: the best extraction technological condition of the Mongolian drug piperine three taste is AI B1C1D1, namely:join 6 times as 65% ethyl alcohol as the raw material for medicine each time,backflow 1 time,each time needs 60min. Conclusion:This method is feasible.
Keywords:Mongolian drag piperine three tastes  Piperine  Orthogonal experiment
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