| 实验性IgA肾病的肝脏改变 |
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| 引用本文： | 董小黎 郑国芬. 实验性IgA肾病的肝脏改变[J]. 首都医科大学学报, 1990, 11(3): 203-205 |
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| 作者姓名： | 董小黎 郑国芬 |
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| 作者单位： | 首都医学院病理解剖学教研室，首都医学院病理解剖学教研室，首都医学院病理解剖学教研室 |
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| 摘 要： | 对实验性四氯化碳性肝硬变所致IgA肾病的大鼠肝脏进行PAP法免疫组织化学染色,以观察肝脏改变。结果表明,用药22-1061大鼠肝窦的枯否氏细胞、肝窦基底膜和汇管区的巨噬细胞以及个别肝细胞浆内均有明显的IgA沉着,IgG着色非常弱。肝脏IgA沉积出现的时间先于肾脏IgA。此外还就肝肾IgA沉积的机理及肝脏IgA沉积与肝脏硬变的关系进行了探讨。
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| 关 键 词： | 肝硬变 IgA沉积物 IgA肾病 |
| 收稿时间： | 1990-01-10 |
Hepatic Lesiens in Experimental IgA Nephropathy |
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| Dong Xiaoli,Zheng Guofen,Wu Zhimin. Hepatic Lesiens in Experimental IgA Nephropathy[J]. Journal of Capital Medical University, 1990, 11(3): 203-205 |
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| Authors: | Dong Xiaoli Zheng Guofen Wu Zhimin |
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| Affiliation: | Dong Xiaoli,Zheng Guofen,Wu Zhimin Department of Patho-anatomy Capital Insitiute of Medicine |
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| Abstract: | Hepatic lesions in experimental IgA nephropathy induced by CC14 cirrhosis of rats were demonsratted by PAP immuno-histoehemical method, IgA was found in the hepatic sinusoids, Kupffer's cells, phagocytes of portal regions and isolated hepatocytes. IgA deposits appeared earlier in the liver than in the kidney. IgG was also found in the hepatic tissues. |
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| Keywords: | cirrnosis IgA deposit IgA nephropathy |
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