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Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients
Authors:Phillippi Julie A  Eskay Michael A  Kubala Adam A  Pitt Bruce R  Gleason Thomas G
Affiliation:aDepartment of Cardiothoracic Surgery, Center for Thoracic Aortic Disease, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;bDepartment of Environmental and Occupational Health, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Abstract:
Keywords:Abbreviations and Acronyms: BAV, bicuspid aortic valve   ECM, extracellular matrix   MMP, matrix metalloproteinase   MT, metallothionein   ROS, reactive oxygen species   rVEGF, recombinant vascular endothelial growth factor   SMC, smooth muscle cell   TAA, thoracic aortic aneurysm   TAV, tricuspid aortic valve   tBHP, t-butyl hydroperoxide   VEGF, vascular endothelial growth factor
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