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Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients |
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| Authors: | Phillippi Julie A Eskay Michael A Kubala Adam A Pitt Bruce R Gleason Thomas G |
| Institution: | aDepartment of Cardiothoracic Surgery, Center for Thoracic Aortic Disease, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;bDepartment of Environmental and Occupational Health, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania |
| Abstract: | |
| Keywords: | Abbreviations and Acronyms: BAV bicuspid aortic valve ECM extracellular matrix MMP matrix metalloproteinase MT metallothionein ROS reactive oxygen species rVEGF recombinant vascular endothelial growth factor SMC smooth muscle cell TAA thoracic aortic aneurysm TAV tricuspid aortic valve tBHP t-butyl hydroperoxide VEGF vascular endothelial growth factor |
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