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造血干细胞移植是目前治疗儿童白血病的重要手段之一。造血干细胞移植的适应证因白血病类型和供者种类不同而有所不同;供者以往以同胞供者为主,目前无关供者移植的生存率已接近同胞供者,半相合移植治疗白血病也越来越被临床所接受;各种细胞辅助治疗逐渐突显优势。造血干细胞移植治疗白血病进展迅速,临床应有所了解。

Advances of hematopoietic stem cell transplantation in the treatment of childhood leukemia

??Hematopoietic stem cell transplantation??HSCT?? is an important method in the treatment of childhood leukemia. The indication of HSCT is different according to the typies of leukemia and donor. In the past a matched sibling donor??MSD?? was the first choice??however??the results in HSCT from unrelated donor??MUD?? have already been close to those from MSD transplant now??and so??haploidentical HSCT for leukemia has been increasingly accepted. A lot of cell therapies have gradually shown the advantages. The advances of HSCT in the treatment of leukemia are important for the clinicians.