18F-FDG PET-CT对结直肠癌诊断及治疗的影响

目的探讨18F-FDG PET-CT检查对结直肠癌诊断及治疗的影响。方法对56例经病理检查确诊的结直肠癌患者行全身PET-CT检查。将入组患者根据其CT表现及PET-CT扫描结果进行分期,并比较2种分期结果。结果 PET-CT检查判断临床分期:56例结直肠癌T分期中,53例PET-CT检查分期判断准确,44例CT检查分期判断准确,PET-CT检查对判断结直肠癌T分期的准确性较CT检查高(χ2=6.235,P=0.024);56例结直肠癌N分期,PET-CT检查判断准确52例,CT检查判断准确43例;PET-CT检查对判断结直肠癌N分期的准确性与CT相比具有显著性差异(χ2=5.617,P=0.033);CT检查发现了15例患者27处转移,PET-CT检查发现了21例患者48处转移,改变了6例患者的M分期。15例患者因PET-CT检查结果而改变了治疗策略,影响率为26.8%。结论 PET-CT检查对结直肠癌的临床分期判断准确性较高。

Impact of 18F-FDG PET-CT on the Diagnosis and Treatment of Colorectal Carcinoma

Objective To evaluate the impact of is F-fluorodeoxyglueose positron emission tomography and computed tomography （JSF-FDG PET-CT） on the diagnosis and clinical therapeutical strategy in patients with colorectal carcinoma. Methods 56 patients with histologically confirmed co]orectal carcinoma received PET-CT scan. The stage and homologous treatment strategy were designed according to CT or PET-CT findings, then analyze the the different stage and management between the two examination ways. Results In the judgement of tumor status, PET-CT were correct in 53 cases,whereas CT were correct in 44 ea- ses and the difference was statistielly significant （ X2 = 6. 235, P = 0.024 ）. In the judgement of nodal status, PET-CT were correct in 52 cases ,whereas CT were correct in 43 cases and the difference was statisticlly significant also （ X2 = 5. 617 ,P =0.033 ）. 27 distant metastases were detected in 15 patients with CT, and 48 distant metastases were detected in 21 patients with PET-CT. PET- CT findings changed the M stage in 6 patients besides the CT examination. The clinical therapeutic strategies were changed in 15 ease due to the results of PET-CT, and the influence rate of PET-CT was 26.8%. Conclusion PET-CT can provide additional useful information that could make significant alteration to clinical stage and treatment plan in patients with colorectal carcinoma