| 乙型肝炎血源疫苗与卡介苗的联合应用 |
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| 引用本文： | 钱水根,虞乐萍,顾曰萍,邱申熊,徐志一,任世玲. 乙型肝炎血源疫苗与卡介苗的联合应用[J]. 现代免疫学, 1988, 0(5) |
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| 作者姓名： | 钱水根 虞乐萍 顾曰萍 邱申熊 徐志一 任世玲 |
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| 作者单位： | 上海医科大学妇产科医院(钱水根，虞乐萍，顾曰萍，邱申熊)，上海医科大学流行病学教研室(徐志一)，上海医科大学流行病学教研室(任世玲) |
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| 摘 要： | 本文观察HBsAg阳性孕妇77例,其新生儿生后当天接种乙肝疫苗,次日接种卡介苗;同期HBsAg阴性孕妇的新生儿8,289例,单接种卡介苗。3个月时结核菌素试验阳转率分别为92.2％、93.4％。卡介苗在乙肝疫苗后接种无干扰作用。
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ADMINISTRATION OF HEPATITIS B PLASMA VACCINE IN COMBINATION WITH BCG |
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| Abstract: | 77 newborns of HBsAg positive carried mothers were immunized with hepatitis B plasma vaccine within 24 hours after delivery and with BCG on the next day.The positive rate of tuberculin test in these babies at 3 months of age was 92.2% as compared to 93.4% in 8289 babies of non-carried mothers to whom BCG alone was given.The hepatitis B vaccine did not seem to interfere the immunogenicity of BCG.The protective efficacy of the hepatitis B vaccine for preventing perinatal transmission of hepatitis B virus in the babies of carried mothers,when used in combination with BCG,ranged between 67-89% The protective efficacy of hepatitis B vaccine for babies of carried mothers,when used alone,was estimated to be 71-74%,as it was reported elsewhere.Thus,the use of BCG did not interfere the immunogenicity of hepatitis B vaccine. |
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