| 曲唑酮与阿米替林治疗抑郁症的对照观察 |
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| 引用本文： | 马玲,付慧鹏,张勇. 曲唑酮与阿米替林治疗抑郁症的对照观察[J]. 临床心身疾病杂志, 2002, 0(3) |
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| 作者姓名： | 马玲 付慧鹏 张勇 |
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| 作者单位： | 河南省郑州市第八人民医院 450006(马玲，付慧鹏)，河南省郑州市第八人民医院 450006(张勇) |
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| 摘 要： | 为比较曲唑酮与阿米替林治疗抑郁症的疗效和副反应,将符合CCMD-3抑郁症诊断标准的患者随机分为两组,分别给予曲唑酮和阿米替林治疗,并于治疗前及治疗后第1、2、4、6周分别用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表(CGI-SI)及副反应量表(TESS)评定。结果,曲唑酮组显效率62.5％,总有效率为87.5％;阿米替林组分别为57.2％和86,7％。HAMD评分两组间疗效无显著差(P>0.05)。不良反应:曲唑酮表现为镇静,阿米替林为抗胆碱能症状。结论;曲唑酮是一种疗效与阿米替林相当,而副作用较轻的抗抑郁药。
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| 关 键 词： | 曲唑酮 阿米替林 抑郁症 |
The Control Studies of Trazodonc and Amitriptyline in Depression |
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| Ma Ling,Fu Hui-peng,Zhang Yong. The Control Studies of Trazodonc and Amitriptyline in Depression[J]. Journal of Clinical Psychosomatic Diseases, 2002, 0(3) |
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| Authors: | Ma Ling Fu Hui-peng Zhang Yong |
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| Abstract: | To compare the clinical efficacy and side reactions of amitriptyline and trazodone in the treatment of depression, patients who met CCMD-III-R criteria for depression were randomly divided into amitriptyline group and trazodone group, curative effects and side reactions were evaluated with the HAMD, CGI-SI and TESS before and after treatment. Results; There was no significant difference in HAMD for curative effect between the two groups. The side reactions were seda-ties in trazodone group and anticholine symptom in amitriptyline gruop, respectively. Conclusion: Compared with amitriptyline, trazpdone has similiar curative effect and mild side reaction. |
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| Keywords: | Trazodone Amitriptyline Depression |
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