| 降钙素基因相关肽与高血压 |
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| 引用本文： | 邓盘月,李元建. 降钙素基因相关肽与高血压[J]. 中国药理学通报, 2004, 20(8): 853-856 |
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| 作者姓名： | 邓盘月 李元建 |
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| 作者单位： | 中南大学药学院药理学系,湖南,长沙,410078 |
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| 摘 要： | 感觉神经广泛分布于全身血管组织 ,通过释放多种血管活性神经肽调节心血管功能。降钙素基因相关肽是辣椒素敏感感觉神经的重要肽类递质 ,为目前已知的舒血管作用最强的物质。在高血压患者及多种实验性高血压动物中降钙素基因相关肽的合成和释放均发生改变 ,对高血压的发生、发展起着重要的作用
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| 关 键 词： | 降钙素基因相关肽(CGRP) 高血压 感觉神经 辣椒素 |
| 文章编号： | 1001-1978(2004)08-0853-04 |
| 修稿时间： | 2003-11-14 |
The role of calcitonin gene-related peptide in hypertension |
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| DENG Pan yue,LI Yuan jian. The role of calcitonin gene-related peptide in hypertension[J]. Chinese Pharmacological Bulletin, 2004, 20(8): 853-856 |
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| Authors: | DENG Pan yue LI Yuan jian |
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| Abstract: | The sensory merves innervate blood vessels all over the body and participate in the regulation of cardiovascular function both in the normal state and in the pathophysiology of hypertension through the actions of potent vasodilator neuropeptides Calcitonin gene related peptide, the predominant neurotransmitter in the capsaicin sensitive sensory nerves, plays an important role in the initiation and progression of hypertension via the alterations in its synthesis and release. |
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| Keywords: | calcitonin gene-related peptide (CGRP) hypertension sensory nerves capsaicin |
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