关于眼局部应用激素引起眼压升高的研究现状

激素具有良好的抗炎、抗过敏和免疫抑制、改善新陈代谢等作用,最近几年研究表明,任何给药途径(全身给药、滴眼、结膜下注射、球内或球后注射等)均可引起眼压升高反应,其中以局部点眼最多见,部分患者出现了青光眼性视神经损害、视野缺损和视力下降,导致激素性青光眼,严重者可致视力丧失。

Research advancement on the eye pressure elevated by local applied hormone

The hormone has good functions about anti-inflamma-tion,anti-allergy and immunosuppression,improvement of metabolism. Recently reports indicated that any admini-stration route may cause eye pressure increase,especially by the way of eye dropping. Some patients presented the hormone glaucoma such as glaucoma optic nerve harm,the field of vision damage and the vision decrease. In this review,we research and summary the status about intraocular pressure elevation related with local hormone.