| 降钙素基因相关肽在预处理心肌保护中机制的研究进展 |
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| 引用本文： | 陆姚,张野. 降钙素基因相关肽在预处理心肌保护中机制的研究进展[J]. 国际麻醉学与复苏杂志, 2002, 30(1): 266-268. DOI: 10.3760/cma.j.issn.1673-4378.2009.03.021 |
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| 作者姓名： | 陆姚 张野 |
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| 作者单位： | 安徽医科大学第一附属医院麻醉科,合肥,230022; |
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| 摘 要： | 近年来发现一种新的神经肽即降钙素基因相关肽(calcitonin gene related peptide,CGRP)具有强心、舒张血管的作用,是目前研究的热点.CGRP能防止心肌缺血/再灌注损伤,在预处理即时和延时心肌保护中的研究很多,但是其具体的机制仍不清楚,仍需要进一步的研究.现主要对CGRP在预处理心肌保护中的作用作一综述.
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| 关 键 词： | 降钙素基因相关肽 预处理 心肌 |
Advance in mechanism of calcitonin gene-related peptide in preconditioning-induced cardioprotection |
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| LU Yao,ZHANG Ye. Advance in mechanism of calcitonin gene-related peptide in preconditioning-induced cardioprotection[J]. international journal of anesthesiology and resuscitation, 2002, 30(1): 266-268. DOI: 10.3760/cma.j.issn.1673-4378.2009.03.021 |
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| Authors: | LU Yao ZHANG Ye |
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| Abstract: | A new neuropeptide named calcitonin gene related peptide (CGRP) has been reported recently. With its positive inotropic and vascular relaxative effects, CGRP becomes a focus in the current research. In order to understand CGRP protection a-gainst myocardial ischemia/reperfusion injury, a large number of studies concerning cardioprotection induced by early and delayed preconditioning have been conducted. The specific mechanism of this protection still need further investigate. This article intends to provide a review about the mechanism of CGRP in preconditioning eardioprotection. |
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| Keywords: | Calcitonin gene-related peptidePreconditioningMyocardium |
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