六味地黄丸穴位贴敷治疗慢性疲劳综合征临床研究

目的:观察中药六味地黄丸穴位敷贴五脏背俞穴治疗肝肾阴虚型慢性疲劳综合征(CFS)的临床疗效。方法:将符合纳入标准的CFS患者60例随机分为治疗组对照组各30例。治疗组患者予六味地黄丸为方制成药饼贴敷五脏背俞穴,对照组予针刺五脏背俞穴。两组治疗均为隔日1次,5次为1个疗程,共治疗4个疗程。所有患者治疗前后及治疗期间均运用CFS症状评分表和FS-14评分量表对该疗法进行综合评价。结果:两组治疗后CFS症状评分及FS-14评分两项指标与治疗前比较均有所改善,差异均有统计学意义(P<0.05);治疗组与对照组相比,其CFS症状评分、FS-14总分、FS-14躯体疲劳评分治疗前后的差值无统计学差异(P>0.05),FS脑力疲劳评分有统计学意义(P<0.05)。结论:针对肝肾阴虚型CFS患者,运用六味地黄丸制成药饼穴位贴敷与针刺常规治疗两种方法疗效确切,均可减轻患者的症状,两者总体疗效相当,针刺组在改善患者脑力疲劳症状方面更明显。

Clinical Research on Effect of Acpoint Application in Treating Chronic Fatigue Syndrome

Objective ： To observe the clinical efficacy of acupoint sticking completely back acupoints with Liuwei Dihuang Pill for treatment of liver and kidney Yin deficiency type of CFS. Methods ：60 standard CFS patients were randomly divided into treat- ment group and control group ,30 cases in each. Treatment group patients with liuwei dihuang pill made medicine cake for the par- ty attach back five zang - organs, acupoints sticking 2 - 4 hours/day ; Control group to the five zang - organs back acupoints, acu- puncture retaining needle for 30 minutes. Both two groups were given the treatment every other day,3 times a week and totally 4 weeks one course. After treatment, compared the efficacy of the these two groups with the symptom scale of CFS and Fatigue Scale - 14 （FS - 14）. Results：After the treatment, the symptom scale of CFS and the FS - 14 decreased in both two groups （P 〈 0.05 ）,there was statistical significance（P 〈 O. 05 ）. Compared the treatment and control group part and the total scale of the FS- 14（ P 〉 O. 05 ）, while there was statistical significance in mental fatigue part of FS - 14 （ P 〈 O. 05 ）. Conclusion ： To the liver and kidney Yin deficiency type of CFS, acupoint sticking with liuwei dihuang pill and the acupuncture has the almost the same effect. While the acupuncture had the better effect on the mental fatigue than acupoint sticking method.