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白英提取物的抗氧化作用研究
引用本文:谢永芳,廖系晗,梁亦龙,舒坤贤.白英提取物的抗氧化作用研究[J].时珍国医国药,2006,17(6):899-900.
作者姓名:谢永芳  廖系晗  梁亦龙  舒坤贤
作者单位:1. 重庆邮电学院生物信息学院,重庆,400065
2. 重庆市中药研究所,重庆,400065
基金项目:国家自然科学基金资助项目(No.30000084)重庆市教委自然科学基金资助项目重庆邮电学院青年科技基金(No.A2005-22)
摘    要:目的研究白英提取物的抗氧化作用。方法小鼠分别口服给予白英水提取物,1次/d,连续给药15 d,取血测过氧化物酶(POD)活性,取血、肝、肾测超氧化物歧化酶(SOD)活性,脂质过氧化产物(MDA)含量。结果白英提取物可显著提高POD活性及血、肝、肾的SOD活性,并减少血、肝、肾组织中MDA的含量。结论白英提取物有提高小鼠体内过氧化物酶、超氧化物歧化酶活性及减少脂质过氧化产物的抗氧化作用。

关 键 词:白英  过氧化物酶  超氧化物歧化酶  脂质过氧化物  抗氧化
文章编号:1008-0805(2006)06-0899-02
收稿时间:2005-08-01
修稿时间:2006-01-15

Study of Anti-oxiddant Effects of Extracts of Solanum lyratum Thumb
XIE Yong-fang,LIAO Xi-han,LIANG Yi-long,SHU Kun-xian.Study of Anti-oxiddant Effects of Extracts of Solanum lyratum Thumb[J].Lishizhen Medicine and Materia Medica Research,2006,17(6):899-900.
Authors:XIE Yong-fang  LIAO Xi-han  LIANG Yi-long  SHU Kun-xian
Institution:1. College of Bioinformatic , Chongqing University of Post and Telecom , Chongqing 400065, China ; 2. Chongqing Institue of Chinese Materia Medica , Chongqing 400065, China
Abstract:ObjectiveTo study on the anti-oxiddant effects of extracts of Solanum lyratum Thunb.MethodsMice were treated by extracts of Solanum lyratum Thunb.one time a day continuously for 15 days.Blood peroxidase(POD),superoxide dismutase(SOD) and malondialdehyde(MDA) levers of blood,liver,kidney were determined.ResultsPOD and SOD significantly increased and MAD decreased in the mice treated with extracts of Solanum lyratum Thunb.ConclusionThe experiment results indicate that extracts of Solanum lyratum Thunb.can increase the activity of POD and SOD and reduce the activity of MAD in the mice.
Keywords:Solanum lyratum Thunb    POD  SOD  MDA  Antioxidation
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