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囊膜剥脱综合征的研究进展
引用本文:Chen L,Wang NL. 囊膜剥脱综合征的研究进展[J]. 中华眼科杂志, 2010, 46(6): 572-576. DOI: 10.3760/cma.j.issn.0412-4081.2010.06.023
作者姓名:Chen L  Wang NL
作者单位:北京同仁眼科中心,北京市眼科学与视觉科学重点实验室,首都医科大学附属北京同仁医院,100730
摘    要:囊膜剥脱综合征是一种与年龄相关的全身性细胞外基质疾病,在发病过程中,可继发青光眼,加速白内障的进展,使术中和术后并发症明显增多.囊膜剥脱综合征的发生机制至今尚不清楚,因此,有必要就目前对囊膜剥脱综合征的临床、分子病理学、遗传学等方面的研究进展进行综述,旨在加深对囊膜剥脱综合征发病机制的认识.

关 键 词:虹膜色素剥脱综合征  患病率  遗传学

Progress of research on exfoliation syndrome
Chen Ling,Wang Ning-li. Progress of research on exfoliation syndrome[J]. Chinese Journal of Ophthalmology, 2010, 46(6): 572-576. DOI: 10.3760/cma.j.issn.0412-4081.2010.06.023
Authors:Chen Ling  Wang Ning-li
Affiliation:Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Abstract:Exfoliation syndrome is an age-related systemic disorder of extracellular matrix,which is associated with a rapid progress of cataract resulting in the increased incidence of complications during operation and post-operation of cataract.The exact pathogenesis of exfoliation syndrome is still unclear.The purpose of this review is to discuss the recent progress in the clinical diagnosis,cell biology,molecular biology,and an improved knowledge of genetics,which will provide a better understanding of the mechanism behind this disorder.
Keywords:Exfoliation syndrome  Prevalence  Genetics
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