淋巴结转移率为基础的TRM分期在胃癌预后中的价值

  目的  探讨淋巴结转移率（RML）为基础的TRM分期在胃癌预后中价值。  方法  采用Cox回归进行多因素生存分析，通过比较-2log likelihood值和hazard ratio（HR）值，比较TRM分期和TNM分期在胃癌预后评价中的差异。  结果  单因素分析显示年龄，肿瘤大小，肿瘤部位，大体分型，分化类型，肿瘤浸润深度（UICC T分期），淋巴结转移数目分期（UICC N分期），淋巴结转移率（RML）分期，TNM分期和TRM分期与胃癌预后相关；相同TRM分期中不同TNM分期预后差异无统计学意义，而TNM分期ⅢB和ⅢC期中不同TRM分期预后差异有统计学意义。Cox多因素分析显示TRM分期与TNM分期相比，HR值较高而-2log likelihood值较小。  结论  TRM分期较TNM分期能更好的预测胃癌患者的预后。 

Prognostic Value of the Tumor-Ratio-Metastasis Staging System for Gastric Cancer

  Objective  To evaluate the prognostic value of the tumor-ratio-metastasis (TRM) staging system in gastric cancer.  Methods  Survival analysis was performed using the Cox regression model. Two parameters were used to compare the differences between the tumor-node-metastasis (TNM) and TRM staging systems and between the -2log likelihood and the hazard ratio (HR).  Results  Univariate analysis showed that age, tumor size, tumor location, macroscopic type, histological grade, tumor depthUnion for International Cancer Control (UICC) T stage], number of metastatic lymph nodes (UICC N stage), ratio between metastatic and dissected lymph nodes (RML) staging system, and the TNM and TRM staging systems were related to the survival status. Under the same TRM staging score, no statistical differences were found among the results of different TNM staging cases. However, for TNM stages ⅢB and ⅢC cases, statistical differences were observed in the survival among patients with different TRM staging scores. The Cox multivariate analysis showed that the TRM staging system had a higher HR and a smaller -2log likelihood, compared with the TNM staging system.  Conclusion  The TRM staging system is superior to the TNM staging system in the prognostic assessment of gastric cancer.