Slice-selective images of free radicals in mice with modulated field gradient electron paramagnetic resonance (EPR) imaging. |
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Authors: | Hideo Sato-Akaba Haruhiko Abe Hirotada Fujii Hiroshi Hirata |
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Affiliation: | Department of Electrical Engineering, Yamagata University, Yonezawa, Yamagata, Japan. |
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Abstract: | Continuous wave (CW) electron paramagnetic resonance (EPR) imaging can be used to obtain slice-selective images of free radicals without measuring three-dimensional (3D) projection data. A method that incorporated a modulated magnetic field gradient (MFG) was combined with polar field gradients to select a slice in the subject noninvasively. The slice-selective in vivo EPR imaging of triarylmethyl radicals in the heads of live mice is reported. 3D surface-rendered images were successfully obtained from slice-selective images. In the experiment in mice, a slice thickness of 1.8 mm was achieved. |
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Keywords: | slice selection EPR imaging free radicals in vivo imaging modulated field gradient |
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