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Immunoreactive renin variations during fertile and infertile hyperstimulated cycles with in-vitro fertilization and embryo transfer or gamete intra-Fallopian transfer
Authors:Cedard, L.   Mignot, Th.M.   Guichard, A.   Boyer, P.   Zorn, J.R.
Affiliation:In Vitro Fertilization Programme Baudelocque, St-Vincent-de-Paul and U. 166 Institut National de la Sant? et de la Recherche M?dicale (INSERM) Maternit? Baudelocque, 123 boulevard de Port-Royal, 75014 Paris, France
Abstract:The concentrations of prorenin (PR) and active renin (AR) weredetermined sequentially during ovarian hyperstimulated cyclesfor in-vitro fertilization -embryo transfer or gamete intra-Fallopiantransfer. AR and PR increased during the early luteal phaseand PR was highly correlated with the progesterone concentration.In fertile cycles, AR increased more rapidly after HCG injectionand AR and PR levels were significantly higher during the lateluteal phase. These results confirm the role of the renin angiotensinsystem in ovarian physiology.
Keywords:plasma renin/prorenin/variation/IVF - ET/GIFT
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