个体化饮食干预对糖耐量减低病人动脉硬化的影响

目的:研究个体化饮食干预对糖耐量减低病人动脉硬化的影响。方法:选择2008年5月至2009年5月于本院门诊及体检中心体检确诊的糖耐量减低病人358例,随机分为干预组185例和对照组173例。所有病人均建立患者个人健康档案,干预组进行个体化饮食干预,对照组只进常规饮食。所有患者均于治疗前和治疗12个月后查空腹血糖、餐后2h血糖、血压、体重指数、血脂、踝臂指数、眼底动脉及颈动脉硬化程度,分析所得数据。结果:复查诊断为糖尿病的患者:对照组15例(8.7%),干预组8例(4.3%),干预组的显著低于对照组(P0.05);干预组眼底动脉积分(1.42±0.45)分∶(2.23±0.53)分]、颈动脉硬化积分(1.84±0.37)分∶(2.87±0.76)分]均明显低于对照组,踝臂指数(1.13±0.09)∶(0.87±0.13)%]显著高于对照组(P均0.05)。结论:个体化加强饮食干预能够改善糖耐量减低病人的动脉硬化程度,延缓动脉硬化进程。

Effects of personal diet intervention on arteriosclerosis in patients with impaired glucose tolerance

Objective： To investigate the effects of personal diet intervention on arteriosclerosis in patients with impaired glucose tolerance. Methods： A total of 358 patients with impaired glucose tolerance from hospital were randomly divid- ed into intervention group （n： 185） and control group （n= 173）. Patients in intervention group were treated with per- sonal diet while patients in control group accepted normal diet. All patients accepted detection of fasting blood glucose, blood glucose 2 h after diet, ankle--braehial index and degree of arteriosclerosis in ocular fundus artery and carotid ar- tery before and after therapy 12 months. Results： Patients diagnosed as diabetes in intervention group was lower （4.3%, 8/185） than that of control group （8.70%, 15/173）, P〈0.0,5. Compared with control group, the ocular fun- dus artery scores （2.23±0.53） vs. （1.42±0.45）], carotid atherosclerosis scores （2.87±0.76） vs. （1.84± 0.37）] in intervemion group were significandy lower, but ankle-brachial index （1.13±0. 09） vs. （0.87±0.13）] increased （P〈0. 05 all）. Conclusion. Personal diet inter vention can improve arteriosclerosis in patients with impaired glucose tolerance and slow down its progression.