| 紫苏子药材质量标准研究 |
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| 引用本文： | 谷丽华,林晨,吴弢,侴桂新,王峥涛. 紫苏子药材质量标准研究[J]. 中国中药杂志, 2010, 35(16): 2087-2090 |
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| 作者姓名： | 谷丽华 林晨 吴弢 侴桂新 王峥涛 |
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| 作者单位： | 1. 上海中医药大学,中药研究所,中药标准化教育部重点实验室,中药新资源与质量标准综合评价国家中医药管理局重点研究室,上海,201210;上海中药标准化研究中心,上海,201210
2. 湖北中医学院,药学院,湖北,武汉,430065 |
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| 基金项目： | 国家药典委员会项目(YD-192);上海市教委科研基金项目(07CZ037);上海市重点学科建设项目(Y0301);上海市科委中药现代化专项基金(08DZ1970103) |
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| 摘 要： | 目的:制定紫苏子药材质量标准。方法:采用生药学研究,水分测定法,薄层色谱法及HPLC色谱法。结果:对紫苏子的显微特征进行了描述;对15个不同产地的紫苏子活性成分迷迭香酸、木犀草素和芹菜素进行了薄层定性鉴别,并对迷迭香酸进行了HPLC定量研究。结论:通过研究制定了紫苏子的质量控制标准。
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| 关 键 词： | 紫苏子 质量标准 迷迭香酸 木犀草素 芹菜素 TLC HPLC |
| 收稿时间： | 2009-06-18 |
Quality specification of Perillae Fructus |
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| GU Lihu,LIN Chen,WU Tao,CHOU Guixin and WANG Zhengtao. Quality specification of Perillae Fructus[J]. China Journal of Chinese Materia Medica, 2010, 35(16): 2087-2090 |
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| Authors: | GU Lihu LIN Chen WU Tao CHOU Guixin WANG Zhengtao |
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| Affiliation: | MOE Key Laboratory for Standardization of Chinese Medicines and State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Materia Medica, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, China;Shanghai Research and Development Center for Standardization of Chinese Medicines, Shanghai 201210, China;Hubei University of Chinese Medicine, Wuhan 430065, China;MOE Key Laboratory for Standardization of Chinese Medicines and State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Materia Medica, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, China;Shanghai Research and Development Center for Standardization of Chinese Medicines, Shanghai 201210, China;MOE Key Laboratory for Standardization of Chinese Medicines and State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Materia Medica, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, China;Shanghai Research and Development Center for Standardization of Chinese Medicines, Shanghai 201210, China;MOE Key Laboratory for Standardization of Chinese Medicines and State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Materia Medica, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, China;Shanghai Research and Development Center for Standardization of Chinese Medicines, Shanghai 201210, China |
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| Abstract: | To improve the quality control specification of Perillae Fructus, the identification methods and assay were developed. Rosmarinic acid, luteolin and apigenin in the sample were identified by TLC. The content of rosmarinic acid was determined by HPLC. The linear calibration curve of rosmarinic acid was obtained in the ranges of 19.4-194.2 g·L-1(R2=0.999 9). The arerage coveriy (n=9) for the assay was 99.8%(RSD 3.6%). The established methods are accuracy, sensitivity and reproducible, and can be used for the quality control of Perillae Fructus. |
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| Keywords: | Perillae Fructus quality specification rosmarinic acid luteolin apigenin TLC HPLC |
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