| 锌诱导小鼠肝产生金属硫蛋白的实验研究 |
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| 引用本文： | 刘晓梅,孙志伟,石龙,邱炳源,李春英,王忠伟.锌诱导小鼠肝产生金属硫蛋白的实验研究[J].中国公共卫生,2000,16(4):315-316. |
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| 作者姓名： | 刘晓梅 孙志伟 石龙 邱炳源 李春英 王忠伟 |
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| 作者单位： | 1. 白求恩医科大学预防医学院,长春,130021
2. 吉林省劳动卫生与职业病防治研究所 |
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| 基金项目： | 国家自然科学基金资助课题 |
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| 摘 要： | 给小鼠腹腔注射Ｚｎ盐，应用镉饱和法测定肝金属硫蛋白的量。结果显示：连续３天给小鼠低于致死量的锌盐与其诱导产生肝ＭＴ的量间存在时间－效应、剂量－效应关系。
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| 关 键 词： | 锌 肝 金属硫蛋白 时间－效应 剂量－效应 |
Study on hepatic metallothionein of mice injected with zinc |
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| Liu Xiaomei.Study on hepatic metallothionein of mice injected with zinc[J].Chinese Journal of Public Health,2000,16(4):315-316. |
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| Authors: | Liu Xiaomei |
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| Abstract: | The dose effect and time effect relationships of metallothionein(MT)were studied from the liver of mice injected with zinc and MT measured by cadmiumsaturation methods.It showed that there was a relation between the hepatic MT and zinc dose below the letal dose of mice.The hepatic MT of mice increased in 12hours,decreased after 24 hours and reached normal level after 3 days.The more zinc,the more hepatic MT at certain scope of doses. |
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| Keywords: | Zinc Hepatic MT Dose effect relationship Time effect relationship |
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